Fake news and the seven sins of capital: a metaphorical analysis of vices in the context of the COVID-19 pandemic. / As fake news e os sete pecados do capital: uma análise metafórica de vícios no contexto pandêmico da COVID-19.

Health crises spawn "sins" and moral deformities in society that are evident when they emerge but had seemed to be dormant to collective awareness before. Through the metaphor of the seven capital sins, the article analyzes the phenomenon of fake news in the social media and in the scenario of the COVID-19 pandemic: the lust of sensationalism through the seduction and exploitation of vulnerabilities associated with fear of death; gluttony for confirmatory contents that spread untruths in the attempt to turn versions into facts; the catechism of denialism, fueling wrath or hate in restrictive epistemic environments; the greed of new technologies in the attention economy through engagement as a new commodity; competition for the spotlights of media visibility and derived gains that incite pride and envy in researchers that confuse public meaning with fake research, in a cycle that feeds sensationalism, gluttony, hate, and greed in attention capitalism. Finally, sloth is portrayed as the capital sin of opting for communicative inaction. In the comfort of bubbles, people renounce dialogue out of aversion to dissent, settling for positions of epistemic comfort. In short, the fake news phenomenon in the COVID-19 pandemic is portrayed here as the convergence of various vices that materialize as misinformation, in the communicative vacuity of the moments in which we are obliged to address each other to share our worldviews.

As crises sanitárias fazem surgir "pecados" e deformidades morais da sociedade que, embora evidentes quando despontam, pareciam antes dormentes à percepção coletiva. Por meio da metáfora dos sete pecados capitais, o texto analisa o fenômeno das fake news nas mídias sociais e no cenário da pandemia da COVID-19. A luxúria do sensacionalismo, que é viciosa pela sedução e exploração de vulnerabilidades ligadas ao medo da morte; a gula, por conteúdos de confirmação que disseminam inverdades no empenho de converter versões em fatos; a catequese do negacionismo gerando o ódio em ambientes epistêmicos restritivos; a ganância das novas tecnologias da economia da atenção pelo engajamento como nova commodity; a competição pelos holofotes da visibilidade midiática e ganhos derivados que incitam a soberba e a inveja dos pesquisadores que confundem o senso público com as fake researches - o que, em ciclo, nutrirão o sensacionalismo, gula, ódios e as ganâncias do capitalismo da atenção. Por fim, a preguiça é retratada como o vício capital dos que optam pela inação comunicativa. No conforto das bolhas renunciam ao diálogo por aversão ao dissenso, acomodando-se em posições de conforto epistêmico. Em síntese, o fenômeno das fake news na pandemia da COVID-19 é aqui retratado como a confluência de diversos vícios que se materializam como desinformação, na vacuidade comunicativa dos momentos nos quais somos obrigados a nos dirigir uns aos outros para partilhar nossas visões do mundo.

Las crisis sanitarias sacan a la luz "pecados" y deformidades morales de la sociedad que, aunque son evidentes cuando emergen, antes parecían latentes a la percepción colectiva. A través de la metáfora de los siete pecados capitales, el texto analiza el fenómeno de las fake news en las redes sociales y en el escenario de la pandemia del COVID-19. La lujuria del sensacionalismo que se ensaña con la seducción y la explotación de las vulnerabilidades ligadas al miedo a la muerte; la gula por los contenidos de confirmación que difunden las falsedades en el afán de convertir las versiones en hechos; el catecismo del negacionismo que genera el odio en entornos epistémicos restrictivos; la avaricia de las nuevas tecnologías de la economía de la atención por el compromiso como nueva commodity; la competencia por los focos de la visibilidad mediática y las ganancias derivadas que incitan a la soberbia, y la envidia de los investigadores que confunden el sentido público con falsas investigaciones -que, en ciclo, alimentarán el sensacionalismo, la gula, el odio y la avaricia del capitalismo de la atención. Por último, la pereza se presenta como el vicio capital de quienes optan por la inacción comunicativa. En la comodidad de sus burbujas renuncian al diálogo por aversión al disenso, instalándose en posiciones de comodidad epistémica. En resumen, el fenómeno de las fake news en la pandemia del COVID-19 se retrata aquí como la confluencia de varios vicios que se materializan como desinformación en la vacuidad comunicativa de momentos en los que nos vemos obligados a dirigirnos unos a otros para compartir nuestras visiones del mundo.

Variability in case fatality rate risk due to Covid-19 according to health services provider in Mexico City hospitals.

OBJECTIVE: To describe differences in Case Fatality Rate (CFR) for Covid-19 among healthcare subsystems in Mexico City between March and December 2020. MATERIALS AND METHODS: This is a retrospective secondary data analysis from the National Epidemiological Surveillance System data of Covid-19 cases. Information about health provider institutions was retrieved from the Catalogue of Health Establishments (CLUES). Logistic regressions were fitted to determine the association between health subsystems and mortality associated to Covid-19. The analyses were divided between hospitalized and ambulatory patients. RESULTS: The probability of dying from Covid-19 was higher among those treated at Instituto Mexicano del Seguro Social (IMSS) (Hospitalized:OR=5.11, Ambulatory:OR=36.57), Instituto de Se-guridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE) (Hospitalized:OR=2.10, Ambulatory:OR=9.19), Secretaría de Salud (SS) (Hospitalized:OR=1.94, Ambulatory:OR=5.29) or other public institutions (Hospitalized: OR=1.70, Ambulatory:OR=9.56) than in those treated in private in-stitutions. CONCLUSIONS: Differences in healthcare quality and access between health subsystems are profound. It is imperative to increase the capacity and quality of the different health subsystems to improve health outcomes.

COVID-19-associated mucormycosis, diabetes and steroid therapy: Experience in a single centre in Western Mexico.

BACKGROUND: COVID-19-associated mucormycosis (CAM) has emerged as a challenging complication as the current pandemic has increased the population requiring treatment with corticosteroids. CAM has caused a massive outbreak in India, reported to be causing cases in Iran, Egypt and The Netherlands. OBJECTIVES: To describe CAM cases occurring in a single centre in Western Mexico. METHODS: Our group carried out a retrospective study from May 2020 to May 2021 to identify CAM cases in patients with previous COVID-19 diagnosis. RESULTS: Six CAM cases occurred in a single centre in Western Mexico during the study period, most of them with diabetes (n = 5/6) and all received corticosteroid therapy even when only three had severe COVID-19. After analysing local COVID-19 burden, it was estimated that in this region, CAM was 300 times more frequent among COVID individuals than the estimates for general population. CONCLUSION: Similar to large reports in India and other countries, CAM cases reported in this study were diagnosed in individuals with diabetes, hyperglycaemic status and with history of previous use of corticosteroids. Identifying these individuals at risk can help the early identification of CAM. In addition, strict glycaemic control and avoidance of unnecessary corticosteroid in non-severe COVID-19 cases could help in preventing this complicated fungal infection.

Auricular Neuromodulation for Mass Vagus Nerve Stimulation: Insights From SOS COVID-19 a Multicentric, Randomized, Controlled, Double-Blind French Pilot Study.

Importance: An exacerbated inflammatory response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is believed to be one of the major causes of the morbidity and mortality of the coronavirus disease 2019 (COVID-19). Neuromodulation therapy, based on vagus nerve stimulation, was recently hypothesized to control both the SARS-CoV-2 replication and the ensuing inflammation likely through the inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cells pathway and could improve the clinical outcomes as an adjunct treatment. We proposed to test it by the stimulation of the auricular branch of the vagus nerve, i.e., auricular neuromodulation (AN), a non-invasive procedure through the insertion of semipermanent needles on the ears. Objective: The aim of this study was to assess the effect of AN on the clinical outcomes in patients affected by COVID-19. Design, Setting, and Participants: A multicenter, randomized, placebo-controlled, double-blind clinical trial included 31 patients with respiratory failure due to COVID-19 requiring hospitalization. Within 72 h after admission, patients received either AN (n = 14) or sham neuromodulation (SN, n = 15) in addition to the conventional treatments. Main Outcome and Measures: The primary endpoint of the study was the rate of a clinical benefit conferred by AN at Day 14 (D14) as assessed by a 7-point Clinical Progression Scale. The secondary endpoint of the study was the impact of AN on the rate of transfer to the intensive care unit (ICU) and on the survival rate at D14. Results: The AN procedure was well-tolerated without any reported side effects but with no significant improvement for the measures of both primary (p > 0.3) and secondary (p > 0.05) endpoints at the interim analysis. None of the AN-treated patients died but one in the SN group did (81 years). Two AN-treated patients (73 and 79 years, respectively) and one SN-treated patient (59 years) were transferred to ICU. Remarkably, AN-treated patients were older with more representation by males than in the SN arm (i.e., the median age of 75 vs. 65 years, 79% male vs. 47%). Conclusion: The AN procedure, which was used within 72 h after the admission of patients with COVID-19, was safe and could be successfully implemented during the first two waves of COVID-19 in France. Nevertheless, AN did not significantly improve the outcome of the patients in our small preliminary study. It is pertinent to explore further to validate AN as the non-invasive mass vagal stimulation solution for the forthcoming pandemics. Clinical Trial Registration: [https://clinicaltrials.gov/], identifier [NCT04341415].

Inflammatory and Prothrombotic Biomarkers Associated With the Severity of COVID-19 Infection.

Among COVID-19 hospitalized patients, high incidence of alterations in inflammatory and coagulation biomarkers correlates with a poor prognosis. Comorbidities such as chronic degenerative diseases are frequently associated with complications in COVID-19 patients. The aim of this study was to evaluate inflammatory and procoagulant biomarkers in COVID-19 patients from a public hospital in Mexico. Blood was sampled within the first 48 h after admission in 119 confirmed COVID-19 patients that were classified in 3 groups according to oxygen demand, evolution and the severity of the disease as follows: 1) Non severe: nasal cannula or oxygen mask; 2) Severe: high flow nasal cannula and 3) Death: mechanical ventilation eventually leading to fatal outcome. Blood samples from 20 healthy donors were included as a Control Group. Analysis of inflammatory and coagulation biomarkers including D-dimer, interleukin 6, interleukin 8, PAI-1, P-selectin and VWF was performed in plasma. Routine laboratory and clinical biomarkers were also included and compared among groups. Concentrations of D-dimer (14.5 ± 13.8 µg/ml) and PAI-1 (1223 ± 889.6 ng/ml) were significantly elevated in severe COVID-19 patients (P < 0.0001). A significant difference was found in interleukin-6, PAI-1 and P-selectin in non-severe and healthy donors when compared to Severe COVID-19 and deceased patients (P < 0.001). VWF levels were also significantly different between severe patients (153.5 ± 24.3 UI/dl) and non-severe ones (133.9 ± 20.2 UI/dl) (P < 0.0001). WBC and glucose levels were also significantly elevated in patients with Severe COVID-19. Plasma concentrations of all prothrombotic biomarkers were significantly higher in patients with a fatal outcome.

Essay on Pandementia: when the characters and microbes of science fiction jump off the screen and invade the planet

RESUMEN Este ensayo crítico acerca de las declaraciones sobre la técnica y la vida en el planeta COVID-19 propone una reflexión ético-filosófica de los efectos de la pandemia. Trata de entender, atribuir significados y criticar las referencias a la pandemia, especialmente en Brasil, en momentos especialmente dramáticos, debido a la sinergia entre la grave enfermedad que afecta al país y al planeta, y un gobierno que se destaca por su gigantesca incapacidad para hacer frente a la calamidad. Este texto fue escrito en el periodo de "cuarentena" brasileña, desde mediados de marzo hasta fines de abril de 2020. Es un momento en el que los hechos nos golpean y no dejan de atormentarnos, y se vive a diario bajo el terrible dominio de esta pandemia. Así, este texto se caracteriza por estar elaborado en medio de un contexto social marcado por los esfuerzos de control y atención de la salud de los afectados, a pesar del complejo marco político actual y de las profundas dificultades económicas del país. ABSTRACT This essay intends to carry out an ethical and philosophical reflection on the effects of the emergency contingencies of the COVID-19 pandemic. With a focus on Brazil, it seeks to understand, critique, and attribute meaning to references to the pandemic, in particularly dramatic moments brought about by the synergy produced between the serious disease affecting the country and the world and a government that stands out for its remarkable unwillingness and inability to deal with this calamity. This text was written during the Brazilian "quarantine," which lasted from mid-March to late April, 2020. During this period, we were bombarded by facts that never ceased to haunt us, and lived each day under the terrible dominion of the pandemic. Therefore, this text was written in the midst of a social context marked by control efforts, with great attention directed at the health of those affected, despite the complex political framework and serious economic difficulties facing the country.

Essay on Pandementia: when the characters and microbes of science fiction jump off the screen and invade the planet

RESUMEN Este ensayo crítico acerca de las declaraciones sobre la técnica y la vida en el planeta COVID-19 propone una reflexión ético-filosófica de los efectos de la pandemia. Trata de entender, atribuir significados y criticar las referencias a la pandemia, especialmente en Brasil, en momentos especialmente dramáticos, debido a la sinergia entre la grave enfermedad que afecta al país y al planeta, y un gobierno que se destaca por su gigantesca incapacidad para hacer frente a la calamidad. Este texto fue escrito en el periodo de "cuarentena" brasileña, desde mediados de marzo hasta fines de abril de 2020. Es un momento en el que los hechos nos golpean y no dejan de atormentarnos, y se vive a diario bajo el terrible dominio de esta pandemia. Así, este texto se caracteriza por estar elaborado en medio de un contexto social marcado por los esfuerzos de control y atención de la salud de los afectados, a pesar del complejo marco político actual y de las profundas dificultades económicas del país. ABSTRACT This essay intends to carry out an ethical and philosophical reflection on the effects of the emergency contingencies of the COVID-19 pandemic. With a focus on Brazil, it seeks to understand, critique, and attribute meaning to references to the pandemic, in particularly dramatic moments brought about by the synergy produced between the serious disease affecting the country and the world and a government that stands out for its remarkable unwillingness and inability to deal with this calamity. This text was written during the Brazilian "quarantine," which lasted from mid-March to late April, 2020. During this period, we were bombarded by facts that never ceased to haunt us, and lived each day under the terrible dominion of the pandemic. Therefore, this text was written in the midst of a social context marked by control efforts, with great attention directed at the health of those affected, despite the complex political framework and serious economic difficulties facing the country.

[Essay on Pandementia: when the characters and microbes of science fiction jump off the screen and invade the planet]. / Ensayo sobre la pandemencia: cuando los personajes y microbios de la ciencia ficción salen de la película.

This essay intends to carry out an ethical and philosophical reflection on the effects of the emergency contingencies of the COVID-19 pandemic. With a focus on Brazil, it seeks to understand, critique, and attribute meaning to references to the pandemic, in particularly dramatic moments brought about by the synergy produced between the serious disease affecting the country and the world and a government that stands out for its remarkable unwillingness and inability to deal with this calamity. This text was written during the Brazilian "quarantine," which lasted from mid-March to late April, 2020. During this period, we were bombarded by facts that never ceased to haunt us, and lived each day under the terrible dominion of the pandemic. Therefore, this text was written in the midst of a social context marked by control efforts, with great attention directed at the health of those affected, despite the complex political framework and serious economic difficulties facing the country.

Este ensayo crítico acerca de las declaraciones sobre la técnica y la vida en el planeta COVID-19 propone una reflexión ético-filosófica de los efectos de la pandemia. Trata de entender, atribuir significados y criticar las referencias a la pandemia, especialmente en Brasil, en momentos especialmente dramáticos, debido a la sinergia entre la grave enfermedad que afecta al país y al planeta, y un gobierno que se destaca por su gigantesca incapacidad para hacer frente a la calamidad. Este texto fue escrito en el periodo de "cuarentena" brasileña, desde mediados de marzo hasta fines de abril de 2020. Es un momento en el que los hechos nos golpean y no dejan de atormentarnos, y se vive a diario bajo el terrible dominio de esta pandemia. Así, este texto se caracteriza por estar elaborado en medio de un contexto social marcado por los esfuerzos de control y atención de la salud de los afectados, a pesar del complejo marco político actual y de las profundas dificultades económicas del país.

COVID-19, fake news, and the sleep of communicative reason producing monsters: the narrative of risks and the risks of narratives COVID-19, las fake news y el sueño de la razón comunicativa generando monstruos: el relato de los riesgos y los riesgos de los relatos

Resumo: Desde o início do surto da COVID-19, percebe-se uma crescente tensão provocada pela dimensão pandêmica de uma doença que trouxe severos impactos epidemiológicos e desdobramentos socioculturais e políticos. Em condições ideais de comunicação pública as autoridades deveriam alinhar-se a um regime de total transparência com informações abundantes e de compreensão facilitada para gerar credibilidade, confiança e parceria com as mídias. Nos hiatos de versões aceitáveis e em meio a indeterminações, os indivíduos tornam-se experts de si mesmos, consumindo fake news e reproduzindo narrativas de risco falaciosas com consequências desastrosas. Discutem-se diversos aspectos ligados às fake news e ao uso da razão comunicativa por autoridades públicas, citando o caso do Irã e estabelecendo paralelos com o fenômeno da antivacinação e suas consequências. Descreve-se o desafio do direcionamento coordenado da sociedade por meio de informações, competindo com pastiches pseudo-científicos que proliferam em ritmo frenético na vacuidade de dados oficiais. Levanta-se, assim, a seguinte questão: quais modelos comunicativos deveriam pautar a narrativa oficial para gerar condições de colaboração e parceria com as mídias? Que impactos tais modelos teriam na proliferação das narrativas enganosas às quais recorrem os cidadãos em crise de orientações pertinentes? Conclui-se que é também papel do governo lançar mão de sua ampla visibilidade para gerar referências de segurança sob o primado da razão comunicativa sensível às genuínas interrogações da sociedade. Em síntese, produzir em escala monumental referenciais responsáveis, norteados por elementos de ética da responsabilidade alinhados ao bem comum. Resumen: Desde el inicio del brote de la COVID-19, se percibe una creciente tensión provocada por la dimensión pandémica de una enfermedad que ha traído consigo severos impactos epidemiológicos y despliegues socioculturales y políticos. En condiciones ideales de comunicación pública, las autoridades deberían estar alineadas a un régimen de total transparencia con información abundante y de comprensión fácil para generar credibilidad, confianza y un clima de colaboración con los medios de comunicación. Ante la carencia de versiones aceptables e imbuidos por indeterminaciones, los individuos se convierten en expertos de sí mismos, consumiendo fake news y reproduciendo relatos de riesgo falaces con consecuencias desastrosas. Se discuten diversos aspectos vinculados a las fake news y al uso de la razón comunicativa por parte de las autoridades públicas, citando el caso da Irán, y estableciendo paralelismos con el fenómeno antivacunas y sus consecuencias. Se describe el desafío para orientar coordinadamente a la sociedad mediante información, compitiendo con pastiches pseudo-científicos, que proliferan con un ritmo frenético ante la vacuidad de los datos oficiales. De esta forma, se plantea la siguiente pregunta: ¿qué modelos comunicativos deberían pautar el relato oficial, con el fin de generar condiciones de colaboración y alianza con los medios de comunicación? ¿Qué impactos tendrían tales modelos en la proliferación de relatos engañosos a los que recurren los ciudadanos que no disponen de información pertinente? Se concluye que es también papel del gobierno utilizar su amplia visibilidad para generar referentes seguros con la ayuda de la primacía de la razón comunicativa, sensible a los genuinos interrogantes de la sociedad. En resumen, generar a gran escala referentes responsables, orientados por elementos de la ética de la responsabilidad alineados con el bien común. Abstract: Since the beginning of the COVID-19 outbreak, the world has witnessed growing tension from the pandemic dimension of a disease with severe epidemiological impacts and wide-reaching sociocultural and political spinoffs. In ideal conditions of public communication, the authorities would be aligned with a totally transparent system supplying abundant information and ease of understanding to generate credibility, confidence, and partnership with the media. In the hiatuses of acceptable versions and in the midst of indeterminations, individuals become their own experts, consuming fake news and reproducing fallacious risk narratives with disastrous consequences. The article discusses various aspects of fake news and the use of communicative reason by public authorities, citing the case of Iran and drawing parallels with the antivaccination movement and its consequences. The authors address the challenge of coordinated orientation of society with information, competing with pseudo-scientific pastiches that proliferate at breakneck speed in the absence of official data. All this raises the following question: which communication models should back the official narrative to create the conditions for collaboration and partnership with the media? What impacts would such models have on the proliferation of misleading narratives that citizens turn to during crises of appropriate orientation? The authors conclude that it is also the government's role to use its broad visibility to create references of safety under the primacy of communicative reason, sensitive to society's genuine questions and concerns. In short, government should produce responsible references on a monumental scale, oriented by the ethics of accountability in line with the common good.

COVID-19, fake news, and the sleep of communicative reason producing monsters: the narrative of risks and the risks of narratives. / COVID-19, as fake news e o sono da razão comunicativa gerando monstros: a narrativa dos riscos e os riscos das narrativas.

Since the beginning of the COVID-19 outbreak, the world has witnessed growing tension from the pandemic dimension of a disease with severe epidemiological impacts and wide-reaching sociocultural and political spinoffs. In ideal conditions of public communication, the authorities would be aligned with a totally transparent system supplying abundant information and ease of understanding to generate credibility, confidence, and partnership with the media. In the hiatuses of acceptable versions and in the midst of indeterminations, individuals become their own experts, consuming fake news and reproducing fallacious risk narratives with disastrous consequences. The article discusses various aspects of fake news and the use of communicative reason by public authorities, citing the case of Iran and drawing parallels with the antivaccination movement and its consequences. The authors address the challenge of coordinated orientation of society with information, competing with pseudo-scientific pastiches that proliferate at breakneck speed in the absence of official data. All this raises the following question: which communication models should back the official narrative to create the conditions for collaboration and partnership with the media? What impacts would such models have on the proliferation of misleading narratives that citizens turn to during crises of appropriate orientation? The authors conclude that it is also the government's role to use its broad visibility to create references of safety under the primacy of communicative reason, sensitive to society's genuine questions and concerns. In short, government should produce responsible references on a monumental scale, oriented by the ethics of accountability in line with the common good.